Transforming Clinical Practice with PRECISE-CIP: A Patient-Facing Solution
The PRECISE-CIP project is a revolutionary collaboration between NalaGenetics, NUH, and NUS under Singapore's national precision medicine initiative to transform patient care through personalized pharmacogenomics in clinical practice.
Product Used
- Pharmacogenomics (PGx)
Organization
- National University Hospital (NUH)
- National University of Singapore (NUS)
Sample Size
1,500 patients
Location
Singapore
Background
The Pharmacogenomics Clinical Implementation Pilot (PRECISE-CIP) project is a groundbreaking collaboration between NalaGenetics, National University Hospital (NUH), and National University of Singapore (NUS). Launched as part of PRECISE, Singapore's national precision medicine initiative, this pilot program is revolutionizing how pharmacogenomics (PGx) is used in clinical practice. With the potential to transform patient care, we're working together to deliver personalized medicine that leads to better health outcomes for patients across Singapore.
Challenges
While pharmacogenomics (PGx) offers the potential to optimize treatments, a significant portion of genetic data remains untapped due to challenges in integrating it into clinical practice. The PRECISE pilot project addresses these gaps, aiming to provide healthcare professionals with the tools to make data-driven, personalized treatment decisions, improving patient safety and therapeutic outcomes in Singapore. Key challenges that need to be addressed include:
Fragmented EHR (Electronic Health Report) System
Singapore's healthcare clusters face challenges with integration and automation, hindering seamless data flow.
Patient Access
The need for a user-friendly app to allow patients to easily access and understand their pharmacogenomic reports.
Missing Tools
Lack of automated haplotype calling software and actionable recommendations for dosages and alternative medications.
Our Solutions
We integrate Nala Clinical Decision Support™ (CDS) to provide real-time, actionable PGx insights, enabling healthcare providers to make personalized treatment decisions. Combined with real-time updates and secure cloud storage, CDS ensures efficient, data-driven care for patients. Additionally, we've implemented several features to further enhance healthcare delivery:
Real-Time Report Updates
AWS-backed real-time updates ensure PGx reports are instantly available to physicians, providing up-to-date insights for improved treatment decisions.
AWS Data Storage & Compliance
The app uses AWS cloud for secure, compliant data storage, ensuring protection under ISO 27001 standards and scalability for future growth.
Interactive Mobile App for Patient Access
A user-friendly app allows patients to easily view their PGx reports, while physicians can scan a QR code for quick report access, enhancing collaboration.
SingPass Integration
The app integrates with SingPass for secure, easy access, ensuring patient data protection while providing seamless login for users.
Outcomes and Ongoing Impact
Enhanced Patient Engagement
Over 1,500 patients are actively using the app to view their PGx results, empowering them to make informed decisions.
Optimized Prescribing
Healthcare providers have improved prescribing practices, reducing the risk of adverse drug reactions based on actionable PGx insights.
Ongoing Growth
The platform is expanding continuously, with new drug-gene pairs added and regular updates to the knowledge base, supported by AWS cloud services to ensure it remains current and efficient.
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